Nephrotic syndrome is a kidney disorder that causes your body to excrete too much protein in your urine.
Nephrotic syndrome is usually caused by damage to the clusters of small blood vessels in your kidneys that filter waste and excess water from your blood. Nephrotic syndrome causes swelling, especially in your feet and ankles, and increases the risk of other health problems. Nephrotic syndrome can increase your risk of infections and blood clots.
Some of the signs and symptoms of nephrotic syndrome are:
- Severe swelling, particularly around your eyes and in your ankles and feet.
- Weight gain due to excess fluid retention.
- Fatigue.
- Loss of appetite.
Factors that increase your risk of nephrotic syndrome include:
- Certain diseases and conditions increase your risk of developing nephrotic syndromes, such as diabetes, lupus and other kidney diseases.
- Certain medications that can cause nephrotic syndrome include nonsteroidal anti-inflammatory drugs and drugs used to fight infections.
- Some of the infections that increase the risk of nephrotic syndrome include HIV, hepatitis B, hepatitis C, and malaria.
Possible complications of nephrotic syndrome include:
- Blood clots.
- High blood cholesterol and elevated blood triglycerides.
- Poor nutrition.
- High blood pressure.
- Acute kidney failure.
- Chronic kidney disease.
- Infections.
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